Teaching cases
Every case is fictional and invented for teaching. No case describes a real patient, and the model is the fsaverage template, not anyone's anatomy. Each case sets the model; the answers are on the structure pages, where every statement is sourced.
1. Small lesion at the left hand knob
Fictional teaching caseA fictional right-handed adult has a small lesion on the left precentral gyrus at the knob-shaped hand segment. Locate the region on the template and review its eloquence grade.
Questions
- Which deficit would injury to this cortex cause, and on which side of the body?
- Which arterial territory covers the lateral precentral convexity?
- What intraoperative technique is used near motor cortex?
Answers, with sources: precentral gyrus, corticospinal tract
2. Left inferior frontal gyrus, opercular part
Fictional teaching caseA fictional adult has a lesion in the left pars opercularis. Handedness and language dominance have not been tested.
Questions
- Why is this region graded eloquent only conditionally?
- What does the template not tell you about this individual?
- How variable is the location of essential language sites?
Answers, with sources: pars opercularis, pars triangularis
3. Posterior medial superior frontal gyrus
Fictional teaching caseA fictional adult has a lesion on the medial surface of the posterior left superior frontal gyrus.
Questions
- Which functional area lies here, and what syndrome can follow its resection?
- How does the time course differ from injury to primary motor cortex?
Answers, with sources: superior frontal gyrus, precentral gyrus
4. Left insular lesion
Fictional teaching caseA fictional adult has a lesion confined to the left insular cortex. Use the inflated surface to see the insula without the opercula.
Questions
- Which arterial branches supply the insula, and which of them reach the corona radiata?
- Which deep arteries limit resection medially?
Answers, with sources: insula
5. Left thalamic lesion
Fictional teaching caseA fictional adult has a small lesion in the left thalamus. The cortex is shown as glass.
Questions
- Name the four main thalamic arterial territories.
- Why is the thalamus graded eloquent?
Answers, with sources: thalamus
6. Lesion next to the corticospinal tract
Fictional teaching caseA fictional adult has a deep left frontal lesion close to the descending motor pathway. Tracts are shown with the cortex as glass.
Questions
- Through which structures does the corticospinal tract descend?
- What is the intraoperative reference for its position, and what role does tractography play?
Answers, with sources: corticospinal tract, precentral gyrus
Read about this
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The arteries of the brain and their territories, how flow is regulated, what a stroke destroys minute by minute, and the trials that changed treatment.
Intermediate
- Language and speech
Where language lives in the brain, why it is not the same as thought, and how AI language models and speech implants are changing the field.
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- The motor system
How the brain turns intention into movement, from the redrawn motor homunculus to the laws of reaching and the technology that restores it.
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- Brain–computer interfaces
How implants like BrainGate and Neuralink read intention from motor cortex, the maths of decoding, and the race to restore speech and movement.
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